Lawson Laboratory
Research

 

 

 


A hallmark of the vascular system is the diversity in endothelial cell phenotypes in different anatomical locations (see table at right). These distinct phenotypes are particularly tailored for the functional requirements in these different tissues. How this differentiation process occurs is unknown, but there is growing evidence that specification of these endothelial cell types may begin during embryonic development.

 

 

Endothelial differentiation: vascular bed diversity