Postdoctoral positions are available in the Lawson Lab at the University of Massachusetts Medical School to study the molecular and cellular mechanisms of vascular development using the zebrafish as a model system. We are interested in multiple aspects of endothelial cell biology including: how endothelial identity is established, how blood flow impacts gene expression, how endothelial cells interpret growth factor signaling in vivo, and what controls periendothelial differentiation and cross-talk. To address these areas of investigation, we take full advantage of the benefits of the zebrafish including the application of in vivo imaging by 2-photon microscopy, genetic manipulation through the use of programmable nucleases, and development of transgenic sensor lines for visualizing signaling outputs. For examples see the following:
Nature (2007) 445:781-784.
Nature Biotechnology (2008) 26:695-701.
Genes and Development (2009) 23:2272-7.
Nature (2010) 464:1196-200.
Dev. Biol (2010) 357:450-462.
Development (2011) 138:4555-4564.
Developmental Cell (2012) 22:418-429.
Development (2014) 141:1544-1552.
Applicants must be highly motivated and technically accomplished as documented by exceptional publication record and hold a PhD in a related area of study. Ideal candidates will have demonstrated experience in standard and advanced molecular biology approaches. Experience with model organisms is beneficial, but not required. Candidates with bioinformatics experience together with wet bench skills would be ideal.
Please email CV and reprints of relevant publications to the contact information below. Applicants accepted for initial consideration will be subsequently contacted for letters of reference.
Nathan D. Lawson, PhD
Department of Molecular, Cell and Cancer Biology
University of Massachusetts Medical School
Lazare Research Building, Room 617
364 Plantation Street
Worcester, MA 01605